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Berberine is a chemical found in several plants including European barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree tumeric. Recent research (Complement Ther Med. 2019 Oct;46:81-86) shows that it may be useful to fight inflammation. The authors reviewed five studies and found that giving berberine could reduce CRP levels (C-reactive protein, a chemical that increases when there is inflammation). The authors concluded, “This meta-analysis showed berberine supplementation may ameliorate the state of chronic inflammation. Patients with cardiovascular disease and diabetes are two important groups which may benefit from berberine supplementation. Further well-designed investigations with larger samples are needed to ascertain the long-term effects of berberine on chronic inflammation.”