A study appearing in Cancer Chemotherapy and Phamacology (2001;47(Suppl.):S55-S63) looked at 1,242 patients with colorectal cancer. The subjects were divided into two groups; 616 were given oral enzymes. Of the 616, 182 received oral enzymes only another 405 used other complimentary treatments and 29 failed to follow their protocol. Of the 626 who did not receive enzymes, 229 used other complimentary treatments, 29 did not follow their protocols and 368 acted as controls.

Of the 1,242 subjects, 1,162 received surgery with 526 receiving chemotherapy and 218 receiving radiation therapy after the surgery. Subjects who received oral enzymes after radiation or chemotherapy suffered to fewer adverse reactions to the cancer treatment. This represents a significant improvement in the quality of life for these patients. A few of the subjects (about 3%) had mild side effects to the enzyme therapy, mostly mild gastrointestinal complaints.