A study that involved 1,550 young subjects (aged 3-22) suffering from frequent headaches was published in Headache (2007; 47(1): 73-80). CoQ10 deficiency is common in headache patients. Approximately 75% of the subjects in this group was found to have a deficiency in CoQ10, almost half of those had levels below the reference range. The patients with low CoQ10 levels were supplemented with CoQ10 dosed between 1-3 mg/kg per day. After 97 days, 250 of the subjects were reexamined. The plasma levels of CoQ10 improved and the frequency of their headaches decreased. Over 46% of the subjects had a 50% reduction in headache frequency.
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