A small study involving 13 patients, published in the American Journal of Psychiatry (September, 1996) showed that inositol may be useful for patients with obsessive-compulsive disorder. It was a double-blind, placebo-controlled crossover study. One group of subjects was given 18 grams per day of inositol. After six weeks, the group taking the inositol had a significantly lower score on the Yale-Brown Obsessive Compulsive Scale than did the placebo group.