A review of previous research, called a meta-analysis, was published in the Annals of Medicine (2009 Jan 16.:1-10) looked at the effect omega-3 supplementation had on patients with myocardial infarction. The review included eight clinical trials, with a total of 20,997 patients. Overall, it was found that in patients who have had a prior myocardial infarction, omega-3 fatty acid supplementation can reduce the chance of sudden cardiac death.