Research appearing in Alimentary and Pharmacological Therapeutics (Volume 40, Issue 1, July 2014, Pages: 51–62) looked at probiotic supplementation in patients with irritable bowel syndrome (IBS). A single center, randomized, double-blind, placebo-controlled study looked at 186 patients with IBS. Subjects received either a probiotic or a placebo over the 12 weeks of the study.  Results were determined by an IBS severity score (IBS-SSS) between probiotic vs. placebo at week 12. The mean difference in the IBS-SSS was statistically significant (-35.0). The authors conclude, “These results suggest this probiotic confers benefit in IBS and deserves further investigation.”