Research appearing in Experimental Physiology (2008 Dec;93(12):1263-72) looked at the effect vitamin E supplementation had on inflammation in mice. Mice were divided to receive either vitamin E or a placebo for three days. The mice were then injected with a bacterial toxin, designed to induce inflammation (E. coli lipopolysaccharide). Chemicals that indicate inflammation (cytokines) were found at much lower levels in the vitamin E group than they were in the control group.